Vitamin D Levels And Insulin Resistance In Male Type 2 Diabetics At The Metabolic Research Unit Of The University College Hospital, Ibadan

📄 Project Abstract

BACKGROUND: A number of studies have shown a high percentage of insufficient vitamin D levels in humans in the North American, European and Asian regions. Various research works have also shown that insufficient vitamin D levels play a major role in the pathogenesis of chronic non-infective 8 illnesses like diabetes mellitus and cancer. This study was aimed at assessing the vitamin D status and glucose homeostasis in male type 2 diabetics and normal controls. METHODS: This comparative cross-sectional study included 80 confirmed type2 diabetic male patients and 49 normal male controls. All subjects with serum creatinine >1.5mg/dl or acute illness were excluded from the study. Serum 25 hydroxy vitamin D, fasting serum C-peptide and fasting plasma glucose levels were measured in both study groups. RESULTS: This study showed a significant difference between mean 25-OH vitamin D levels of 36.55ng/ml in the diabetic group and 42.96ng/ml in the control group (p= 0.001). All four 25-OH vitamin...