TOXICOLOGICAL AND ANTI-HYPERGLYCAEMIC PROPERTIES OF AQUEOUS LEAF EXTRACT OF PERSEA AMERICANA MILL (LAURECEAE) IN NORMOGLYCAEMIC AND ALLOXAN-INDUCED HYPERGLYCAEMIC WISTAR RATS

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📄 Project Abstract

Diabetes mellitus has become a global health burden leading to an increase in the search for herbal anti-hyperglycaemic agents as alternative to synthetic ones. Persea americana popularly known as avocado pear have been known for its nutritional and medicinal properties. The leaves of this plant are used in Eastern Nigeria especially in Anambra state for the management of Diabetes Mellitus. This study was aimed at evaluating the toxicological and anti-hyperglycaemic properties of aqueous leaf extract of P. americana Mill. (laureceae) in normoglycaemic and alloxan-induced hyperglycaemic Wistar rats. Preliminary phytochemical screening, acute toxicity and sub-chronic toxicity and anti-hyperglycaemic studies of the extract were carried out. Preliminary phytochemical screening revealed the presence of saponins, steroids, flavonoids, tannins, alkaloids, cardiac glycosides, triterpenoids and carbohydrates whereas anthraquinones and cyanogenetic glycosides were absent. The oral median lethal ...

🔍 Key Research Areas Covered
  • ✅ Literature Review & Theoretical Framework
  • ✅ Research Methodology & Data Collection
  • ✅ Data Analysis & Statistical Methods
  • ✅ Findings & Results Discussion
  • ✅ Recommendations & Conclusions
  • ✅ References & Bibliography
📚 Complete Project Structure
Chapter 1: Introduction & Background
  • Problem Statement & Objectives
Chapter 2: Literature Review
  • Theoretical Framework & Related Studies
Chapter 3: Research Methodology
  • Data Collection & Analysis Methods
Chapter 4: Data Analysis & Results
  • Findings & Statistical Analysis
Chapter 5: Discussion & Conclusion
  • Recommendations & Future Research
Appendices: Supporting Documents
  • Questionnaires, Data, References
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"This project provided excellent guidance for my Pharmacology And Therapeutics Project Topics research. The methodology was clear and the data analysis helped me understand the proper approach."

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Full Citation:

STEPHEN CHIADIKAOBI OKAFOR. (). TOXICOLOGICAL AND ANTI-HYPERGLYCAEMIC PROPERTIES OF AQUEOUS LEAF EXTRACT OF PERSEA AMERICANA MILL (LAURECEAE) IN NORMOGLYCAEMIC AND ALLOXAN-INDUCED HYPERGLYCAEMIC WISTAR RATS. African and General Studies, 40, 14858.

Citation Formats:
APA
STEPHEN CHIADIKAOBI OKAFOR. (). TOXICOLOGICAL AND ANTI-HYPERGLYCAEMIC PROPERTIES OF AQUEOUS LEAF EXTRACT OF PERSEA AMERICANA MILL (LAURECEAE) IN NORMOGLYCAEMIC AND ALLOXAN-INDUCED HYPERGLYCAEMIC WISTAR RATS. African and General Studies, 40, 14858.
MLA
STEPHEN CHIADIKAOBI OKAFOR. "TOXICOLOGICAL AND ANTI-HYPERGLYCAEMIC PROPERTIES OF AQUEOUS LEAF EXTRACT OF PERSEA AMERICANA MILL (LAURECEAE) IN NORMOGLYCAEMIC AND ALLOXAN-INDUCED HYPERGLYCAEMIC WISTAR RATS." African and General Studies, vol. 40, , pp. 14858.
Chicago
STEPHEN CHIADIKAOBI OKAFOR. "TOXICOLOGICAL AND ANTI-HYPERGLYCAEMIC PROPERTIES OF AQUEOUS LEAF EXTRACT OF PERSEA AMERICANA MILL (LAURECEAE) IN NORMOGLYCAEMIC AND ALLOXAN-INDUCED HYPERGLYCAEMIC WISTAR RATS." African and General Studies 40 (): 14858.
Full Citation:

STEPHEN CHIADIKAOBI OKAFOR. (). TOXICOLOGICAL AND ANTI-HYPERGLYCAEMIC PROPERTIES OF AQUEOUS LEAF EXTRACT OF PERSEA AMERICANA MILL (LAURECEAE) IN NORMOGLYCAEMIC AND ALLOXAN-INDUCED HYPERGLYCAEMIC WISTAR RATS. African and General Studies, 40, 14858.

Citation Formats:
APA
STEPHEN CHIADIKAOBI OKAFOR. (). TOXICOLOGICAL AND ANTI-HYPERGLYCAEMIC PROPERTIES OF AQUEOUS LEAF EXTRACT OF PERSEA AMERICANA MILL (LAURECEAE) IN NORMOGLYCAEMIC AND ALLOXAN-INDUCED HYPERGLYCAEMIC WISTAR RATS. African and General Studies, 40, 14858.
MLA
STEPHEN CHIADIKAOBI OKAFOR. "TOXICOLOGICAL AND ANTI-HYPERGLYCAEMIC PROPERTIES OF AQUEOUS LEAF EXTRACT OF PERSEA AMERICANA MILL (LAURECEAE) IN NORMOGLYCAEMIC AND ALLOXAN-INDUCED HYPERGLYCAEMIC WISTAR RATS." African and General Studies, vol. 40, , pp. 14858.
Chicago
STEPHEN CHIADIKAOBI OKAFOR. "TOXICOLOGICAL AND ANTI-HYPERGLYCAEMIC PROPERTIES OF AQUEOUS LEAF EXTRACT OF PERSEA AMERICANA MILL (LAURECEAE) IN NORMOGLYCAEMIC AND ALLOXAN-INDUCED HYPERGLYCAEMIC WISTAR RATS." African and General Studies 40 (): 14858.
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Document Details

Author
📁 Field Pharmacology And Therapeutics Project Topics
🏷️ Type Social Sciences project topics
Pages 178 Pages
Words 36848 words
📘 Chapters 1 to 5 Chapters
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