TOXICITY STUDIES ON N-HEXANE AND METHANOL LEAF AND METHANOL SEED EXTRACTS OF JATROPHA CURCAS LINN. IN CHICKS AND MICE

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📄 Project Abstract

Jatropha curcas is a toxic plant commonly used as food and remedy for several diseases. This study was designed to evaluate the protective and therapeutic effects of sodium nitrite, sodium thiosulphate, penicillamine, ethylene diamine tetra-acetic acids (EDTA) and atropine against acute and sub-acute n-hexane leaf, methanol leaf and seed extracts of Jatropha curcas intoxication in 7-14 day old chicks. The oral and intraperitoneal median lethal doses (LD50) of the extracts were performed in mice, one and seven day old chicks. Effect of the antidotes on LD50 and signs of J. curcas extracts intoxication were determined in the acute toxicity study while the therapeutic effect of the antidotes co-administered with the extracts for 7 days were determined in sub-acute toxicity study. Phytochemical, anti-nutritional and elemental analysis of the extracts revealed the presence of secondary metabolites, anti-nutrients and heavy metals. The oral LD50 of hexane and methanol leaf extracts were abov...

🔍 Key Research Areas Covered
  • ✅ Literature Review & Theoretical Framework
  • ✅ Research Methodology & Data Collection
  • ✅ Data Analysis & Statistical Methods
  • ✅ Findings & Results Discussion
  • ✅ Recommendations & Conclusions
  • ✅ References & Bibliography
📚 Complete Project Structure
Chapter 1: Introduction & Background
  • Problem Statement & Objectives
Chapter 2: Literature Review
  • Theoretical Framework & Related Studies
Chapter 3: Research Methodology
  • Data Collection & Analysis Methods
Chapter 4: Data Analysis & Results
  • Findings & Statistical Analysis
Chapter 5: Discussion & Conclusion
  • Recommendations & Future Research
Appendices: Supporting Documents
  • Questionnaires, Data, References
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Full Citation:

OMEIZA BASHIR ALIYU. (). TOXICITY STUDIES ON N-HEXANE AND METHANOL LEAF AND METHANOL SEED EXTRACTS OF JATROPHA CURCAS LINN. IN CHICKS AND MICE. African and General Studies, 40, 14858.

Citation Formats:
APA
OMEIZA BASHIR ALIYU. (). TOXICITY STUDIES ON N-HEXANE AND METHANOL LEAF AND METHANOL SEED EXTRACTS OF JATROPHA CURCAS LINN. IN CHICKS AND MICE. African and General Studies, 40, 14858.
MLA
OMEIZA BASHIR ALIYU. "TOXICITY STUDIES ON N-HEXANE AND METHANOL LEAF AND METHANOL SEED EXTRACTS OF JATROPHA CURCAS LINN. IN CHICKS AND MICE." African and General Studies, vol. 40, , pp. 14858.
Chicago
OMEIZA BASHIR ALIYU. "TOXICITY STUDIES ON N-HEXANE AND METHANOL LEAF AND METHANOL SEED EXTRACTS OF JATROPHA CURCAS LINN. IN CHICKS AND MICE." African and General Studies 40 (): 14858.
Full Citation:

OMEIZA BASHIR ALIYU. (). TOXICITY STUDIES ON N-HEXANE AND METHANOL LEAF AND METHANOL SEED EXTRACTS OF JATROPHA CURCAS LINN. IN CHICKS AND MICE. African and General Studies, 40, 14858.

Citation Formats:
APA
OMEIZA BASHIR ALIYU. (). TOXICITY STUDIES ON N-HEXANE AND METHANOL LEAF AND METHANOL SEED EXTRACTS OF JATROPHA CURCAS LINN. IN CHICKS AND MICE. African and General Studies, 40, 14858.
MLA
OMEIZA BASHIR ALIYU. "TOXICITY STUDIES ON N-HEXANE AND METHANOL LEAF AND METHANOL SEED EXTRACTS OF JATROPHA CURCAS LINN. IN CHICKS AND MICE." African and General Studies, vol. 40, , pp. 14858.
Chicago
OMEIZA BASHIR ALIYU. "TOXICITY STUDIES ON N-HEXANE AND METHANOL LEAF AND METHANOL SEED EXTRACTS OF JATROPHA CURCAS LINN. IN CHICKS AND MICE." African and General Studies 40 (): 14858.
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