THE USE OF GELATIN-ACACIA CO-PRECIPITATE (GELAC) IN THE FORMULATION OF SUSTAINED RELEASE MATRIX TABLETS OF DICLOFENAC SODIUM
📄 Project Abstract
Gums find application in tablet formulation as binder because of their adhesive nature. Natural gums are promising biodegradable polymeric materials. The aim of this study was to prepare a gelatin and acacia co-precipitate (GelAc) to be used as a release retardant in the formulation of sustained release matrix Tablets of diclofenac sodium. Gelatin and acacia solution was precipitated in a ratio of 1:1 using acetone as the precipitating solvent. The dried product was size reduced and the physicochemical properties of the precipitate (GelAc) were evaluated with respect to micromeritics and Fourier Transform Infrared (FT-IR) spectroscopy. FT-IR of GelAc showed no interaction between GelAc and diclofenac. GelAc was used in varying percentages of (10 - 50 %) of the total weight of the Tablet formulation. The formulated tablets were analysed for uniformity of weight tablet thickness and diameter, crushing strength, disintegration time, friability and content uniformity. In-vitro drug release...
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- ✅ Literature Review & Theoretical Framework
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- Problem Statement & Objectives
- Theoretical Framework & Related Studies
- Data Collection & Analysis Methods
- Findings & Statistical Analysis
- Recommendations & Future Research
- Questionnaires, Data, References
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THE USE OF GELATIN-ACACIA CO-PRECIPITATE (GELAC) IN THE FORMULATION OF SUSTAINED RELEASE MATRIX TABLETS OF DICLOFENAC SODIUM
Full Citation:
Mponan Guga. (). THE USE OF GELATIN-ACACIA CO-PRECIPITATE (GELAC) IN THE FORMULATION OF SUSTAINED RELEASE MATRIX TABLETS OF DICLOFENAC SODIUM. African and General Studies, 40, 14858.
Citation Formats:
APA
Mponan Guga. (). THE USE OF GELATIN-ACACIA CO-PRECIPITATE (GELAC) IN THE FORMULATION OF SUSTAINED RELEASE MATRIX TABLETS OF DICLOFENAC SODIUM. African and General Studies, 40, 14858.
MLA
Mponan Guga. "THE USE OF GELATIN-ACACIA CO-PRECIPITATE (GELAC) IN THE FORMULATION OF SUSTAINED RELEASE MATRIX TABLETS OF DICLOFENAC SODIUM." African and General Studies, vol. 40, , pp. 14858.
Chicago
Mponan Guga. "THE USE OF GELATIN-ACACIA CO-PRECIPITATE (GELAC) IN THE FORMULATION OF SUSTAINED RELEASE MATRIX TABLETS OF DICLOFENAC SODIUM." African and General Studies 40 (): 14858.
Full Citation:
Mponan Guga. (). THE USE OF GELATIN-ACACIA CO-PRECIPITATE (GELAC) IN THE FORMULATION OF SUSTAINED RELEASE MATRIX TABLETS OF DICLOFENAC SODIUM. African and General Studies, 40, 14858.
Citation Formats:
APA
Mponan Guga. (). THE USE OF GELATIN-ACACIA CO-PRECIPITATE (GELAC) IN THE FORMULATION OF SUSTAINED RELEASE MATRIX TABLETS OF DICLOFENAC SODIUM. African and General Studies, 40, 14858.
MLA
Mponan Guga. "THE USE OF GELATIN-ACACIA CO-PRECIPITATE (GELAC) IN THE FORMULATION OF SUSTAINED RELEASE MATRIX TABLETS OF DICLOFENAC SODIUM." African and General Studies, vol. 40, , pp. 14858.
Chicago
Mponan Guga. "THE USE OF GELATIN-ACACIA CO-PRECIPITATE (GELAC) IN THE FORMULATION OF SUSTAINED RELEASE MATRIX TABLETS OF DICLOFENAC SODIUM." African and General Studies 40 (): 14858.
Document Details
| Author | Mponan Guga |
|---|---|
| 📁 Field | Pharmaceutics And Pharmaceutical Microbiology project topics |
| 🏷️ Type | Pharmaceutical Sciences Project Topics |
| Pages | 127 Pages |
| Words | 20900 words |
| 📘 Chapters | 1 to 5 Chapters |