The Pathological Features Of Colorectal Carcinoma In Ile-Ife: - A Ten-Year Descriptive Retrospective Study

📄 Project Abstract

Background: Given the improved knowledge of colonic carcinoma worldwide, it is becoming increasingly clear that there are perhaps distinct clinico-pathological, and probably molecular biological, differences between the high-incidence colorectal carcinoma (e.g. in Caucasians) and low-incidence disease (e.g. among black Africans). Whereas there are putative explanations, the bases for the observed differences have however not been well explored. An enduring impediment to this is the subsisting dearth of literature on the pathological characteristics of the disease as it is found among indigenous Africans. Our purpose for carrying out the study was to document the detailed pathological characteristics of the disease amongst our patients. Method: We retrospectively reviewed all cases of colorectal carcinomas seen in the Department of Morbid Anatomy and Forensic Medicine Obafemi Awolowo University Teaching hospitals complex from 1994 to 2003 for site of the lesion in each case, gross appea...