The Effects of Ethanolic Extract of Ocimum gratissimum (Linn.) Leaves on Selected Reproductive Hormones and Insulin on Letrozole Induced Polycystic Ovarian Syndrome in Wistar Rats.pdf

📄 Project Abstract

Medicinal plants are known to possess substances or agents that have therapeutic effects or be used in producing drugs and they have been in use long before the development of orthodox medicine. Many plants used primitively to tackle illnesses have been investigated and show medical importance, an example of which is Ocimum gratissimum (scent leaf) (Idris et al., 2011, Odugbemi, 2006). Ocimum gratissimum is an herbaceous plant belonging to the Lamiacae family (Singh, 2012). It can be found in tropical areas, in the savannah and coastal areas (Singh, 2012). It is cultivated in India, Nigeria, Bengal, Deccan, South Sea Islands, etc. In Nigeria, it is used in the treatment of miscarriage (Ogbe et al., 2009), diarrhea (Sofowora, 1993), and high fever (Oliver, 1960). Ocimum gratissimum possesses certain phytochemicals, that is, biologically active plant compounds that have disease fighting capabilities (Jumare, 2018). They include alkaloids, flavonoids, and polyphenols. (Vieira et al 2001)....