THE AMELIORATIVE EFFECT OF ACACIA SIEBERIANA D.C. METHANOL ROOT BARK EXTRACT ON INDUCED LIVER INJURY AND ITS SUBCHRONIC TOXICITY PROFILE IN RATS
📄 Project Abstract
Acacia sieberiana D.C is traditionally used as a remedy for various ailments including hepatitis. The effect of methanol root bark extract of Acacia sieberiana (ASE) on paracetamol (PCM) - and bile duct ligation (BDL) -induced liver injury wereinvestigated in rats. Rats were divided into six groups (Groups I-VI) of 5 and 6 rats for PCM and BDL, respectively. For the PCM-induced liver injury study, animals were pre-treated with normal saline, silymarin (50mg/kg) and extract (250, 750, 1,500 mg/kg)for 7 days. After the last dose, liver injury was initiated by the administration of PCM (2g/kg). In BDL-induced liver injury study, 6 non-ligated but operated rats were used as control (Group I), Groups I and II received normal saline while Groups III-VI received silymarin (50mg/kg), the extract (125, 250 and 380 mg/kg), respectively, for 7 days. At the end of the experiment, blood and organs were obtainedfor biochemical and histological assay. Results showed the presence of carbohydrates, gly...
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THE AMELIORATIVE EFFECT OF ACACIA SIEBERIANA D.C. METHANOL ROOT BARK EXTRACT ON INDUCED LIVER INJURY AND ITS SUBCHRONIC TOXICITY PROFILE IN RATS
Full Citation:
Miriam Watafua. (). THE AMELIORATIVE EFFECT OF ACACIA SIEBERIANA D.C. METHANOL ROOT BARK EXTRACT ON INDUCED LIVER INJURY AND ITS SUBCHRONIC TOXICITY PROFILE IN RATS. African and General Studies, 40, 14858.
Citation Formats:
APA
Miriam Watafua. (). THE AMELIORATIVE EFFECT OF ACACIA SIEBERIANA D.C. METHANOL ROOT BARK EXTRACT ON INDUCED LIVER INJURY AND ITS SUBCHRONIC TOXICITY PROFILE IN RATS. African and General Studies, 40, 14858.
MLA
Miriam Watafua. "THE AMELIORATIVE EFFECT OF ACACIA SIEBERIANA D.C. METHANOL ROOT BARK EXTRACT ON INDUCED LIVER INJURY AND ITS SUBCHRONIC TOXICITY PROFILE IN RATS." African and General Studies, vol. 40, , pp. 14858.
Chicago
Miriam Watafua. "THE AMELIORATIVE EFFECT OF ACACIA SIEBERIANA D.C. METHANOL ROOT BARK EXTRACT ON INDUCED LIVER INJURY AND ITS SUBCHRONIC TOXICITY PROFILE IN RATS." African and General Studies 40 (): 14858.
Full Citation:
Miriam Watafua. (). THE AMELIORATIVE EFFECT OF ACACIA SIEBERIANA D.C. METHANOL ROOT BARK EXTRACT ON INDUCED LIVER INJURY AND ITS SUBCHRONIC TOXICITY PROFILE IN RATS. African and General Studies, 40, 14858.
Citation Formats:
APA
Miriam Watafua. (). THE AMELIORATIVE EFFECT OF ACACIA SIEBERIANA D.C. METHANOL ROOT BARK EXTRACT ON INDUCED LIVER INJURY AND ITS SUBCHRONIC TOXICITY PROFILE IN RATS. African and General Studies, 40, 14858.
MLA
Miriam Watafua. "THE AMELIORATIVE EFFECT OF ACACIA SIEBERIANA D.C. METHANOL ROOT BARK EXTRACT ON INDUCED LIVER INJURY AND ITS SUBCHRONIC TOXICITY PROFILE IN RATS." African and General Studies, vol. 40, , pp. 14858.
Chicago
Miriam Watafua. "THE AMELIORATIVE EFFECT OF ACACIA SIEBERIANA D.C. METHANOL ROOT BARK EXTRACT ON INDUCED LIVER INJURY AND ITS SUBCHRONIC TOXICITY PROFILE IN RATS." African and General Studies 40 (): 14858.
Document Details
| Author | Miriam Watafua |
|---|---|
| 📁 Field | Pharmaceutical And Medicinal Chemistry Project Topics |
| 🏷️ Type | Pharmaceutical Sciences Project Topics |
| Pages | 108 Pages |
| Words | 20727 words |
| 📘 Chapters | 1 to 5 Chapters |