The Adaptogenic Effect Of Apple Cider Vinegar (Acv) In Chronic Restraint- Stressed Wistar Rats

📄 Project Abstract

Stress is a prime factor for most of the illnesses in human life. Chronic stress exposure has been reported to cause anatomical and physiological brain damage, immunosuppression, infertility and damage to various internal organs. The function of stress hormones; corticosterone and epinephrine is believed to preserve homeostasis but these hormones may turn out to be detrimental in excess or if they persist in blood when no more required. Thirty (30) Adult wistar rats of both sexes (n=30), weighing 150-200 g were divided into 3 groups each consisting of a male and female subgroup and given the following treatments once a day for 21 days: Normal control group received 1 ml distilled water orally, the restraint stress (RS) group were exposed to chronic restraint stress 6 hours daily while the Apple cider vinegar (ACV)-treated group received 4 ml/kg of apple cider vinegar orally in addition to chronic restraint stress 6 hours daily. The rats were sacrificed after the experimental period and...