STUDIES ON ANTIHAEMORRHAGIC AND ANTIBACTERIAL PROPERTIES OF BULB JUICE, ETHANOL AND AQUEOUS EXTRACTS OF ALLIUM SATIVUM LINN. (LILLIACEAE) AGAINST MENINGEAL BACTERIA

📄 Project Abstract

Bacterial meningitis (BM) is a devastating air-borne infectious disease of humans that causes cellular hemorrhagic sepsis, metabolic, neurologic and endocrine disorders and constitutes a serious threat to public health. Where malnutrition is linked to BM, it is a great economic and societal burden accompanied with high morbidity and mortality rates in Sub-Saharan Africa including Nigeria. A. sativum, a medicinal food herb found in Northern Nigeria, has been used in folklore to treat infectious diseases locally including haemorrhagic sepsis and malnutrition. In the present investigation, the antihaemorrhagic and in vitro antibacterial activities of the juice (JEAS), ethanolic (EEAS) and aqueous (AEAS) bulb extracts of A. sativum were evaluated against bacterial meningitis pathogens. The methods employed in this study were validation of phytochemical screening which was done according to standard methods, determination of nutritional composition was carried out using analytical automated...