Serum Adiponectin And Its Relationship To Metabolic Control And Dyslipidaemia In Type 2 Diabetes Mellitus

📄 Project Abstract

Type 2 diabetes mellitus has emerged as a clinical and public health crises in many populations, as Adipocytes produce several adipokines including adiponectin. Adiponectin is an adipokine that is specifically and abundantly expressed in adipose tissue and directly sensitizes the body to insulin. Adiponectin has attracted much attention because of its ant-idiabetic , anti-atherogenic and anti-inflammatory effect and it might become a novel therapeutic agent SUBJECTS AND METHODS To compare the levels of serum adiponectin in type 2 diabetes patients at Lagos University Teaching Hospital with those of age and sex matched controls. A total of 180 subjects (106 females, 74 males) were recruited for this study. The Type 2 diabetic subjects were 110(61.1%) with a mean age of 54.5yr and the control were 70(38.9%) with the mean age of 518yr for type 2 diabetes mellitus. Fasting plasma glucose was estimated using spectrophotometric method, fasting lipid profile was estimated using enzymatic meth...