Seroprevalence Study Of Parvovirus Bi9 Among Normal Blood Donors And Transfused And Non-Transfused Sickle Cell Anaemia Patients At Lagos University Teaching Hospital (Luth

📄 Project Abstract

Parvovirus B19 (PVB19) is one of the emerging agents of transfusion transmissible infection, and occurs in all regions where it has been studied. The aim of the study was to determine the seroprevalence of PVB19 in blood donors and sickle cell anaemia patients and to evaluate the likelihood that transfusion will lead to infection in sickle cell anaemia patients. A cross sectional study was conducted on volunteer blood donors and sickle cell anaemia patients at the Lagos University Teaching Hospital, Lagos Nigeria. Three hundred participants, consisting of 150 blood donors and 150 sickle cell anaemia subjects, who satisfied the inclusion criteria, were enrolled into the study. An Enzyme immunoassay for the in-vitro diagnostic determination of IgG and IgM anti-PVB19 in human serum manufactured by Immuno-Biological Laboratories, (IBL) inc. 8201 central Ave. Minneapolis, USA, was used. Antibody to PVB19 was indicated when the absorbance value is more than 20% above cut off control that was...