SCREENING FOR in vitro ACTIVITY OF EXTRACTS OF Picralima nitida AGAINST Plasmodium falciparum
📄 Project Abstract
The intolerable impact of malaria has been attributed to the increasing resistance of Plasmodium parasite to chemoprophylactic and chemotherapeutic agents. The need for drugs with novel modes of action prompted this research, to discover a new anti-malaria agent from this medicinal plant (Picralima nitida), after discovering that the plant is used traditionally to treat malaria in Nigeria. Crude methanolic and aqueous extracts of the leave, seed and pulp of P.nitida plant were screened for its phytochemical constituents. Different concentrations of the crude extracts were tested on trophozoites mainly ring form. The acute toxicity was also evaluated on white albino mice. The mice were treated orally with single doses of 10,100, 1000, 1600, 2900, 5000, and 8000 mg/kg body weight of Picralima nitida extracts of the leave, seed, and pulp after being starved for 24hrs. The phytochemical screening of aqueous, and methanol extracts of Picralima nitida revealed the presence of Alkaloids, Anth...
🔍 Key Research Areas Covered
- ✅ Literature Review & Theoretical Framework
- ✅ Research Methodology & Data Collection
- ✅ Data Analysis & Statistical Methods
- ✅ Findings & Results Discussion
- ✅ Recommendations & Conclusions
- ✅ References & Bibliography
📚 Complete Project Structure
- Problem Statement & Objectives
- Theoretical Framework & Related Studies
- Data Collection & Analysis Methods
- Findings & Statistical Analysis
- Recommendations & Future Research
- Questionnaires, Data, References
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SCREENING FOR in vitro ACTIVITY OF EXTRACTS OF Picralima nitida AGAINST Plasmodium falciparum
Full Citation:
Unknown Author. (). SCREENING FOR in vitro ACTIVITY OF EXTRACTS OF Picralima nitida AGAINST Plasmodium falciparum. African and General Studies, 40, 14858.
Citation Formats:
APA
Unknown Author. (). SCREENING FOR in vitro ACTIVITY OF EXTRACTS OF Picralima nitida AGAINST Plasmodium falciparum. African and General Studies, 40, 14858.
MLA
Unknown Author. "SCREENING FOR in vitro ACTIVITY OF EXTRACTS OF Picralima nitida AGAINST Plasmodium falciparum." African and General Studies, vol. 40, , pp. 14858.
Chicago
Unknown Author. "SCREENING FOR in vitro ACTIVITY OF EXTRACTS OF Picralima nitida AGAINST Plasmodium falciparum." African and General Studies 40 (): 14858.
Full Citation:
Unknown Author. (). SCREENING FOR in vitro ACTIVITY OF EXTRACTS OF Picralima nitida AGAINST Plasmodium falciparum. African and General Studies, 40, 14858.
Citation Formats:
APA
Unknown Author. (). SCREENING FOR in vitro ACTIVITY OF EXTRACTS OF Picralima nitida AGAINST Plasmodium falciparum. African and General Studies, 40, 14858.
MLA
Unknown Author. "SCREENING FOR in vitro ACTIVITY OF EXTRACTS OF Picralima nitida AGAINST Plasmodium falciparum." African and General Studies, vol. 40, , pp. 14858.
Chicago
Unknown Author. "SCREENING FOR in vitro ACTIVITY OF EXTRACTS OF Picralima nitida AGAINST Plasmodium falciparum." African and General Studies 40 (): 14858.
Document Details
| Author | Unknown Author |
|---|---|
| 📁 Field | Microbiology Project Topics |
| 🏷️ Type | Science project topics |
| Pages | 95 Pages |
| Words | 14688 words |
| 📘 Chapters | 1 to 5 Chapters |