Protective Effect Of Vitamin E On Endosulfan-Induced Oxidative Changes And Associated Neurobehavioural Deficit In Male Wistar Rats

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📄 Project Abstract

Endosulfan is an organochlorine pesticide commonly used to control pests in vegetables, cotton, fruits and other agricultural produce. It is a contact and stomach insecticide toxic to mammals, fish and other aquatic organisms. Several reports have shown that it is a highly neurotoxic agent. The aim of this study was to evaluate the role of brain lipoperoxidation and oxidative stress in sensorimotor and cognitive changes, arising from endosulfan exposure in Wistar rats and the ameliorative potentials of vitamin E. Thirty two (32) male Wistar rats were randomly divided into four groups of eight (8) rats each: group I rats received soya oil at 2 ml/kg body weight; group II rats received vitamin E at a dose of 30 mg/kg body weight; group III rats received endosulfan at a dose of 12 mg/kg; and group IV rats received vitamin E (30 mg/kg) followed by endosulfan (12 mg/kg) after 30 mins. The regimens were administered orally by gavage once daily for 28 days. The rats were examined for neurobeh...

🔍 Key Research Areas Covered
  • ✅ Literature Review & Theoretical Framework
  • ✅ Research Methodology & Data Collection
  • ✅ Data Analysis & Statistical Methods
  • ✅ Findings & Results Discussion
  • ✅ Recommendations & Conclusions
  • ✅ References & Bibliography
📚 Complete Project Structure
Chapter 1: Introduction & Background
  • Problem Statement & Objectives
Chapter 2: Literature Review
  • Theoretical Framework & Related Studies
Chapter 3: Research Methodology
  • Data Collection & Analysis Methods
Chapter 4: Data Analysis & Results
  • Findings & Statistical Analysis
Chapter 5: Discussion & Conclusion
  • Recommendations & Future Research
Appendices: Supporting Documents
  • Questionnaires, Data, References
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APA/MLA formatting with table of contents

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Full Citation:

Hajara Ali Umar. (). Protective Effect Of Vitamin E On Endosulfan-Induced Oxidative Changes And Associated Neurobehavioural Deficit In Male Wistar Rats. African and General Studies, 40, 14858.

Citation Formats:
APA
Hajara Ali Umar. (). Protective Effect Of Vitamin E On Endosulfan-Induced Oxidative Changes And Associated Neurobehavioural Deficit In Male Wistar Rats. African and General Studies, 40, 14858.
MLA
Hajara Ali Umar. "Protective Effect Of Vitamin E On Endosulfan-Induced Oxidative Changes And Associated Neurobehavioural Deficit In Male Wistar Rats." African and General Studies, vol. 40, , pp. 14858.
Chicago
Hajara Ali Umar. "Protective Effect Of Vitamin E On Endosulfan-Induced Oxidative Changes And Associated Neurobehavioural Deficit In Male Wistar Rats." African and General Studies 40 (): 14858.
Full Citation:

Hajara Ali Umar. (). Protective Effect Of Vitamin E On Endosulfan-Induced Oxidative Changes And Associated Neurobehavioural Deficit In Male Wistar Rats. African and General Studies, 40, 14858.

Citation Formats:
APA
Hajara Ali Umar. (). Protective Effect Of Vitamin E On Endosulfan-Induced Oxidative Changes And Associated Neurobehavioural Deficit In Male Wistar Rats. African and General Studies, 40, 14858.
MLA
Hajara Ali Umar. "Protective Effect Of Vitamin E On Endosulfan-Induced Oxidative Changes And Associated Neurobehavioural Deficit In Male Wistar Rats." African and General Studies, vol. 40, , pp. 14858.
Chicago
Hajara Ali Umar. "Protective Effect Of Vitamin E On Endosulfan-Induced Oxidative Changes And Associated Neurobehavioural Deficit In Male Wistar Rats." African and General Studies 40 (): 14858.
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