PHARMACOLOGICAL AND TOXICOLOGICAL STUDIES OF THE METHANOL EXTRACT OF ACACIA ATAXACANTHA LEAF D.C. (LEGUMINOSAE) IN MICE AND RATS
📄 Project Abstract
Acacia ataxacantha is used in traditional medicine for management of pain and inflammation. Literature survey revealed that the safety and efficacy of such uses have not been scientifically validated. The present study was designed to study the pharmacological and toxicological activities of methanol extract of Acacia ataxacantha leaf in mice and rats. The acute and chronic toxicity studies were carried out using Lorke method (1983) and OECD guideline (1995) respectively. The extract was evaluated for analgesic activity using acetic acid, formalin and hot plate induced pain assays. Similarly, anti-inflammatory activity was evaluated using carragenaan and albumin induced inflammation, and antipyretic activity using yeast induced pyrexia. Phytochemical screening revealed the presence of flavonoids, alkaloids, glycosides, phenols, tannins and carbohydrate. The oral median lethal dose (LD50) of the extract in both mice and rats was estimated to be > 5000 mg/kg, while the intraperitoneal LD...
🔍 Key Research Areas Covered
- ✅ Literature Review & Theoretical Framework
- ✅ Research Methodology & Data Collection
- ✅ Data Analysis & Statistical Methods
- ✅ Findings & Results Discussion
- ✅ Recommendations & Conclusions
- ✅ References & Bibliography
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- Problem Statement & Objectives
- Theoretical Framework & Related Studies
- Data Collection & Analysis Methods
- Findings & Statistical Analysis
- Recommendations & Future Research
- Questionnaires, Data, References
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Full Citation:
Medinat Yakubu Abbas. (). PHARMACOLOGICAL AND TOXICOLOGICAL STUDIES OF THE METHANOL EXTRACT OF ACACIA ATAXACANTHA LEAF D.C. (LEGUMINOSAE) IN MICE AND RATS. African and General Studies, 40, 14858.
Citation Formats:
APA
Medinat Yakubu Abbas. (). PHARMACOLOGICAL AND TOXICOLOGICAL STUDIES OF THE METHANOL EXTRACT OF ACACIA ATAXACANTHA LEAF D.C. (LEGUMINOSAE) IN MICE AND RATS. African and General Studies, 40, 14858.
MLA
Medinat Yakubu Abbas. "PHARMACOLOGICAL AND TOXICOLOGICAL STUDIES OF THE METHANOL EXTRACT OF ACACIA ATAXACANTHA LEAF D.C. (LEGUMINOSAE) IN MICE AND RATS." African and General Studies, vol. 40, , pp. 14858.
Chicago
Medinat Yakubu Abbas. "PHARMACOLOGICAL AND TOXICOLOGICAL STUDIES OF THE METHANOL EXTRACT OF ACACIA ATAXACANTHA LEAF D.C. (LEGUMINOSAE) IN MICE AND RATS." African and General Studies 40 (): 14858.
Full Citation:
Medinat Yakubu Abbas. (). PHARMACOLOGICAL AND TOXICOLOGICAL STUDIES OF THE METHANOL EXTRACT OF ACACIA ATAXACANTHA LEAF D.C. (LEGUMINOSAE) IN MICE AND RATS. African and General Studies, 40, 14858.
Citation Formats:
APA
Medinat Yakubu Abbas. (). PHARMACOLOGICAL AND TOXICOLOGICAL STUDIES OF THE METHANOL EXTRACT OF ACACIA ATAXACANTHA LEAF D.C. (LEGUMINOSAE) IN MICE AND RATS. African and General Studies, 40, 14858.
MLA
Medinat Yakubu Abbas. "PHARMACOLOGICAL AND TOXICOLOGICAL STUDIES OF THE METHANOL EXTRACT OF ACACIA ATAXACANTHA LEAF D.C. (LEGUMINOSAE) IN MICE AND RATS." African and General Studies, vol. 40, , pp. 14858.
Chicago
Medinat Yakubu Abbas. "PHARMACOLOGICAL AND TOXICOLOGICAL STUDIES OF THE METHANOL EXTRACT OF ACACIA ATAXACANTHA LEAF D.C. (LEGUMINOSAE) IN MICE AND RATS." African and General Studies 40 (): 14858.
 
                            
                    Document Details
| Author | Medinat Yakubu Abbas | 
|---|---|
| 📁 Field | Pharmacology And Therapeutics Project Topics | 
| 🏷️ Type | Pharmaceutical Sciences Project Topics | 
| Pages | 101 Pages | 
| Words | 18461 words | 
| 📘 Chapters | 1 to 5 Chapters | 
