MULTIDRUG RESISTANCE PROFILE AND METALLO-BETA-LACTAMASE PRODUCTION IN Pseudomonas aeruginosa ISOLATED FROM THE NASAL CAVITY OF CATTLE FROM KARA MARKET OGUN STATE NIGERIA

📄 Project Abstract

Pseudomonas aeruginosa is an ubiquitous, Gram-negative, rod-shaped, monoflagellated bacterium, capable of causing serious infections in immunocompromised host. It is one of the most difficult multidrug resistant microorganisms capable of producing metallo--lactamase (MBL). Though a notorious organism, its identification should not be limited to pigment production alone, as some strains do not produce pigments. This study was aimed at evaluating the increasing prevalence of multidrug resistance profile and MBL production in P. aeruginosa isolated from nasal cavity of cattle from Kara market, Ogun state, Nigeria. In this study, a total of 570 samples were randomly collected from the nasal cavity of healthy male and female cattle using sterile swab sticks. They were tested for the presence of P. aeruginosa on cetrimide agar, observing the agar plates for growth and pigmentation. Further biochemical test and molecular analysis were carried out to further confirm their identity as P. aerugi...