INFLUENCE OF CIMETIDINE ON THE PHARMACOKINETICS OF PARACETAMOL IN HEALTHY SUBJECTS
📄 Project Abstract
Considering the prevalence of peptic ulcer diseases in Nigeria and the popularity of paracetamol as an "household" analgesic, there is the possibility of patients being treated for peptic ulcer to take paracetamol. It is therefore possible for the drug(s) used in the peptic ulcer treatment to influence the pharmacokinetic parameters of paracetamol. The influence of cimetidine (400mg) on the pharmacokinetics of oral single dose (1g) paracetamol was studied in 8 healthy subjects under two protocols (concomitant and delayed paracetamol administration 1 hour after cimetidine). The study was carried out in 3 phases: paracetamol alone (control); paracetamol and cimetidine concomitantly; and paracetamol 1 hour after cimetidine. A wash-out period of 2 weeks was allowed between the phases of the study. The method of residuals was used to obtain the pharmacokinetic parameters using the salivary concentration-time curves generated from the salivary concentration-time data as preliminary data. Sta...
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- ✅ Literature Review & Theoretical Framework
- ✅ Research Methodology & Data Collection
- ✅ Data Analysis & Statistical Methods
- ✅ Findings & Results Discussion
- ✅ Recommendations & Conclusions
- ✅ References & Bibliography
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- Problem Statement & Objectives
- Theoretical Framework & Related Studies
- Data Collection & Analysis Methods
- Findings & Statistical Analysis
- Recommendations & Future Research
- Questionnaires, Data, References
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INFLUENCE OF CIMETIDINE ON THE PHARMACOKINETICS OF PARACETAMOL IN HEALTHY SUBJECTS
Full Citation:
Bala Hina Ahmed. (). INFLUENCE OF CIMETIDINE ON THE PHARMACOKINETICS OF PARACETAMOL IN HEALTHY SUBJECTS. African and General Studies, 40, 14858.
Citation Formats:
APA
Bala Hina Ahmed. (). INFLUENCE OF CIMETIDINE ON THE PHARMACOKINETICS OF PARACETAMOL IN HEALTHY SUBJECTS. African and General Studies, 40, 14858.
MLA
Bala Hina Ahmed. "INFLUENCE OF CIMETIDINE ON THE PHARMACOKINETICS OF PARACETAMOL IN HEALTHY SUBJECTS." African and General Studies, vol. 40, , pp. 14858.
Chicago
Bala Hina Ahmed. "INFLUENCE OF CIMETIDINE ON THE PHARMACOKINETICS OF PARACETAMOL IN HEALTHY SUBJECTS." African and General Studies 40 (): 14858.
Full Citation:
Bala Hina Ahmed. (). INFLUENCE OF CIMETIDINE ON THE PHARMACOKINETICS OF PARACETAMOL IN HEALTHY SUBJECTS. African and General Studies, 40, 14858.
Citation Formats:
APA
Bala Hina Ahmed. (). INFLUENCE OF CIMETIDINE ON THE PHARMACOKINETICS OF PARACETAMOL IN HEALTHY SUBJECTS. African and General Studies, 40, 14858.
MLA
Bala Hina Ahmed. "INFLUENCE OF CIMETIDINE ON THE PHARMACOKINETICS OF PARACETAMOL IN HEALTHY SUBJECTS." African and General Studies, vol. 40, , pp. 14858.
Chicago
Bala Hina Ahmed. "INFLUENCE OF CIMETIDINE ON THE PHARMACOKINETICS OF PARACETAMOL IN HEALTHY SUBJECTS." African and General Studies 40 (): 14858.
Document Details
| Author | Bala Hina Ahmed |
|---|---|
| 📁 Field | Pharmaceutical And Medicinal Chemistry Project Topics |
| 🏷️ Type | Pharmaceutical Sciences Project Topics |
| Pages | 240 Pages |
| Words | 891 words |
| 📘 Chapters | 1 to 5 Chapters |