IN-VITRO AND MOLECULAR STUDIES ON THE RESISTANCE OF P. falciparum TO ANTIMALARIAL DRUGS IN OGUN STATE, SOUTHWESTERN NIGERIA

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📄 Project Abstract

The widespread of drug resistant Plasmodium falciparum has led to a rise in malariaassociated mortality most especially in sub-Saharan Africa. In-vitro and molecular studies were carried out in order to determine the resistant pattern of P. falciparum to antimalarial drugs and some local antimalarial herbs in Ogun State, Southwestern Nigeria. Prevalence of falciparum malaria was determined by microscopic examination of Giemsa-stained blood samples of patients who presented with fever in selected State Hospitals in Ogun State. Antimalarial drug sensitivity of one hundred (100) P. falciparum isolates to chloroquine, amodiaquine, mefloquine, quinine, sulphadoxine/pyrimethamine, artesunate and three local antimalarial herbs: Momordica charantia (Ejirin,) Diospyros monbuttensis (Eegun eja) and Morinda lucida (Oruwo) was determined using the in-vitro microtest (Mark III) technique. For molecular studies and genotyping, DNA was extracted from patient blood using the QiaAmp DNA Blood Minikit e...

🔍 Key Research Areas Covered
  • ✅ Literature Review & Theoretical Framework
  • ✅ Research Methodology & Data Collection
  • ✅ Data Analysis & Statistical Methods
  • ✅ Findings & Results Discussion
  • ✅ Recommendations & Conclusions
  • ✅ References & Bibliography
📚 Complete Project Structure
Chapter 1: Introduction & Background
  • Problem Statement & Objectives
Chapter 2: Literature Review
  • Theoretical Framework & Related Studies
Chapter 3: Research Methodology
  • Data Collection & Analysis Methods
Chapter 4: Data Analysis & Results
  • Findings & Statistical Analysis
Chapter 5: Discussion & Conclusion
  • Recommendations & Future Research
Appendices: Supporting Documents
  • Questionnaires, Data, References
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Full Citation:

OLASEHINDE GRACE IYABO. (). IN-VITRO AND MOLECULAR STUDIES ON THE RESISTANCE OF P. falciparum TO ANTIMALARIAL DRUGS IN OGUN STATE, SOUTHWESTERN NIGERIA. African and General Studies, 40, 14858.

Citation Formats:
APA
OLASEHINDE GRACE IYABO. (). IN-VITRO AND MOLECULAR STUDIES ON THE RESISTANCE OF P. falciparum TO ANTIMALARIAL DRUGS IN OGUN STATE, SOUTHWESTERN NIGERIA. African and General Studies, 40, 14858.
MLA
OLASEHINDE GRACE IYABO. "IN-VITRO AND MOLECULAR STUDIES ON THE RESISTANCE OF P. falciparum TO ANTIMALARIAL DRUGS IN OGUN STATE, SOUTHWESTERN NIGERIA." African and General Studies, vol. 40, , pp. 14858.
Chicago
OLASEHINDE GRACE IYABO. "IN-VITRO AND MOLECULAR STUDIES ON THE RESISTANCE OF P. falciparum TO ANTIMALARIAL DRUGS IN OGUN STATE, SOUTHWESTERN NIGERIA." African and General Studies 40 (): 14858.
Full Citation:

OLASEHINDE GRACE IYABO. (). IN-VITRO AND MOLECULAR STUDIES ON THE RESISTANCE OF P. falciparum TO ANTIMALARIAL DRUGS IN OGUN STATE, SOUTHWESTERN NIGERIA. African and General Studies, 40, 14858.

Citation Formats:
APA
OLASEHINDE GRACE IYABO. (). IN-VITRO AND MOLECULAR STUDIES ON THE RESISTANCE OF P. falciparum TO ANTIMALARIAL DRUGS IN OGUN STATE, SOUTHWESTERN NIGERIA. African and General Studies, 40, 14858.
MLA
OLASEHINDE GRACE IYABO. "IN-VITRO AND MOLECULAR STUDIES ON THE RESISTANCE OF P. falciparum TO ANTIMALARIAL DRUGS IN OGUN STATE, SOUTHWESTERN NIGERIA." African and General Studies, vol. 40, , pp. 14858.
Chicago
OLASEHINDE GRACE IYABO. "IN-VITRO AND MOLECULAR STUDIES ON THE RESISTANCE OF P. falciparum TO ANTIMALARIAL DRUGS IN OGUN STATE, SOUTHWESTERN NIGERIA." African and General Studies 40 (): 14858.
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