`Immunohistochemical Analysis Of Braf (V600e) Mutation And P16 Expression In Malignant Melanoma In Luth: A 10 Year Retrospective Study
📄 Project Abstract
Introduction: Malignant melanoma (MM) is the most lethal of all cutaneous malignancies, accounting for as much as 79% of skin cancer related deaths. Despite its aggressive nature, it remains highly curable if detected early. In blacks however, it is associated with greater morbidity and mortality compared to Caucasians and this has been attributed to advanced stage of disease at presentation. Studies have shown that MM with BRAF V600E mutation as well as those with loss of p16 protein expression are associated with aggressive behaviour and worse prognosis. BRAF kinase inhibitors have also been approved for treatment of BRAF V600E mutant cases while p16 expression is being proposed as a prognostic marker for MM. Aim: The aim of the study was to determine the BRAF (V600E) mutation and loss of p16 expression in MM cases in our hospital within the last 10 years and to correlate these with prognostic markers. Materials and Methods: Formalin-fixed paraffin-embedded (FFPE) tissue blocks and c...
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- ✅ Literature Review & Theoretical Framework
- ✅ Research Methodology & Data Collection
- ✅ Data Analysis & Statistical Methods
- ✅ Findings & Results Discussion
- ✅ Recommendations & Conclusions
- ✅ References & Bibliography
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- Problem Statement & Objectives
- Theoretical Framework & Related Studies
- Data Collection & Analysis Methods
- Findings & Statistical Analysis
- Recommendations & Future Research
- Questionnaires, Data, References
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`Immunohistochemical Analysis Of Braf (V600e) Mutation And P16 Expression In Malignant Melanoma In Luth: A 10 Year Retrospective Study
Full Citation:
Obadofin, Omobolade Olajumoke. (). `Immunohistochemical Analysis Of Braf (V600e) Mutation And P16 Expression In Malignant Melanoma In Luth: A 10 Year Retrospective Study. African and General Studies, 40, 14858.
Citation Formats:
APA
Obadofin, Omobolade Olajumoke. (). `Immunohistochemical Analysis Of Braf (V600e) Mutation And P16 Expression In Malignant Melanoma In Luth: A 10 Year Retrospective Study. African and General Studies, 40, 14858.
MLA
Obadofin, Omobolade Olajumoke. "`Immunohistochemical Analysis Of Braf (V600e) Mutation And P16 Expression In Malignant Melanoma In Luth: A 10 Year Retrospective Study." African and General Studies, vol. 40, , pp. 14858.
Chicago
Obadofin, Omobolade Olajumoke. "`Immunohistochemical Analysis Of Braf (V600e) Mutation And P16 Expression In Malignant Melanoma In Luth: A 10 Year Retrospective Study." African and General Studies 40 (): 14858.
Full Citation:
Obadofin, Omobolade Olajumoke. (). `Immunohistochemical Analysis Of Braf (V600e) Mutation And P16 Expression In Malignant Melanoma In Luth: A 10 Year Retrospective Study. African and General Studies, 40, 14858.
Citation Formats:
APA
Obadofin, Omobolade Olajumoke. (). `Immunohistochemical Analysis Of Braf (V600e) Mutation And P16 Expression In Malignant Melanoma In Luth: A 10 Year Retrospective Study. African and General Studies, 40, 14858.
MLA
Obadofin, Omobolade Olajumoke. "`Immunohistochemical Analysis Of Braf (V600e) Mutation And P16 Expression In Malignant Melanoma In Luth: A 10 Year Retrospective Study." African and General Studies, vol. 40, , pp. 14858.
Chicago
Obadofin, Omobolade Olajumoke. "`Immunohistochemical Analysis Of Braf (V600e) Mutation And P16 Expression In Malignant Melanoma In Luth: A 10 Year Retrospective Study." African and General Studies 40 (): 14858.
Document Details
| Author | Obadofin, Omobolade Olajumoke |
|---|---|
| 📁 Field | Anatomic Pathology project topics |
| 🏷️ Type | Medicine Project topics |
| Pages | 92 Pages |
| Words | 15578 words |
| 📘 Chapters | 1 to 5 Chapters |