GASTRO-INTESTINAL MUCOSAL PROTECTIVE PROPERTIES AND TOXICITY STUDIES ON THE METHANOL ROOT EXTRACT OF WALTHERIA INDICA LINN. (STERCULIACEAE) IN LABORATORY ANIMALS
📄 Project Abstract
Many countries worldwide including Nigeria use different parts of Waltheria indica (leaves, stem-barks, roots and whole plants) to treat various ailments. In Nigeria, Waltheria indica is used to treat gastro-intestinal ulcers, pain, inflammation, diarrhoea, conjunctivitis, anaemia and erectile dysfunction. The aim of this study was to evaluate the gastro-intestinal mucosal protective properties and ascertain the toxicity profile of the methanol root extract of Waltheria indica. Preliminary phytochemical screening was carried out on the extract and the oral median lethal dose (LD50) of the extract was estimated using modified Lorke's (1983) method in rats followed by sub-acute toxicity study using OECD 407, 2008 guidelines where haematological and biochemical indices as well as histology examination of selected organs were carried out. The gastro-protective effect of the extract (250, 500 and 1,000 mg/kg) was evaluated using indomethacin-induced ulcer and pylorus ligation-induced ulcer ...
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GASTRO-INTESTINAL MUCOSAL PROTECTIVE PROPERTIES AND TOXICITY STUDIES ON THE METHANOL ROOT EXTRACT OF WALTHERIA INDICA LINN. (STERCULIACEAE) IN LABORATORY ANIMALS
Full Citation:
Ngyama Blessed Bagobiri- Yem. (). GASTRO-INTESTINAL MUCOSAL PROTECTIVE PROPERTIES AND TOXICITY STUDIES ON THE METHANOL ROOT EXTRACT OF WALTHERIA INDICA LINN. (STERCULIACEAE) IN LABORATORY ANIMALS. African and General Studies, 40, 14858.
Citation Formats:
APA
Ngyama Blessed Bagobiri- Yem. (). GASTRO-INTESTINAL MUCOSAL PROTECTIVE PROPERTIES AND TOXICITY STUDIES ON THE METHANOL ROOT EXTRACT OF WALTHERIA INDICA LINN. (STERCULIACEAE) IN LABORATORY ANIMALS. African and General Studies, 40, 14858.
MLA
Ngyama Blessed Bagobiri- Yem. "GASTRO-INTESTINAL MUCOSAL PROTECTIVE PROPERTIES AND TOXICITY STUDIES ON THE METHANOL ROOT EXTRACT OF WALTHERIA INDICA LINN. (STERCULIACEAE) IN LABORATORY ANIMALS." African and General Studies, vol. 40, , pp. 14858.
Chicago
Ngyama Blessed Bagobiri- Yem. "GASTRO-INTESTINAL MUCOSAL PROTECTIVE PROPERTIES AND TOXICITY STUDIES ON THE METHANOL ROOT EXTRACT OF WALTHERIA INDICA LINN. (STERCULIACEAE) IN LABORATORY ANIMALS." African and General Studies 40 (): 14858.
Full Citation:
Ngyama Blessed Bagobiri- Yem. (). GASTRO-INTESTINAL MUCOSAL PROTECTIVE PROPERTIES AND TOXICITY STUDIES ON THE METHANOL ROOT EXTRACT OF WALTHERIA INDICA LINN. (STERCULIACEAE) IN LABORATORY ANIMALS. African and General Studies, 40, 14858.
Citation Formats:
APA
Ngyama Blessed Bagobiri- Yem. (). GASTRO-INTESTINAL MUCOSAL PROTECTIVE PROPERTIES AND TOXICITY STUDIES ON THE METHANOL ROOT EXTRACT OF WALTHERIA INDICA LINN. (STERCULIACEAE) IN LABORATORY ANIMALS. African and General Studies, 40, 14858.
MLA
Ngyama Blessed Bagobiri- Yem. "GASTRO-INTESTINAL MUCOSAL PROTECTIVE PROPERTIES AND TOXICITY STUDIES ON THE METHANOL ROOT EXTRACT OF WALTHERIA INDICA LINN. (STERCULIACEAE) IN LABORATORY ANIMALS." African and General Studies, vol. 40, , pp. 14858.
Chicago
Ngyama Blessed Bagobiri- Yem. "GASTRO-INTESTINAL MUCOSAL PROTECTIVE PROPERTIES AND TOXICITY STUDIES ON THE METHANOL ROOT EXTRACT OF WALTHERIA INDICA LINN. (STERCULIACEAE) IN LABORATORY ANIMALS." African and General Studies 40 (): 14858.
Document Details
| Author | Ngyama Blessed Bagobiri- Yem |
|---|---|
| 📁 Field | Pharmacology And Therapeutics Project Topics |
| 🏷️ Type | Pharmaceutical Sciences Project Topics |
| Pages | 121 Pages |
| Words | 23030 words |
| 📘 Chapters | 1 to 5 Chapters |