Evaluation Of The Effect Of Camel Milk On Physiological Parameters Of Poloxamer 407 Induced Hyperlipidemic Wistar Rats

📄 Project Abstract

Hyperlipidemia is viewed as a primary mediator of cardiovascular disease. The aim of the study is to evaluate the effect of camel milk on Poloxamer 407 induced hyperlipidemic Wistar rats. Thirty adult male Wistar rats weighing between 150-200g were randomly assigned into six groups of five animals each; Group I: administered distilled water, Group II: Hyperlipidemic negative control, Group III: Hyperlipidemic positive control treated with Atorvastatin (20mg/kg) and Group IV, V and VI:Hyperlipidemic groups treated with camel milk 0.25ml/kg, 0.50ml/kg and 1ml/kg respectively. After three weeks, blood samples drawn fordetermination of Total cholesterol (TC), Triglyceride(TG),High Density Lipoprotein (LDL), Low Density Lipoprotein(LDL), Malondialdhyde(MDA), Catalase(CAT) Superoxide Dismutase(SOD) and Gluthatione Peroxidase(GPx), Total Protein, Albumin, Globulin, A/G ratio, Alkaline Phospatase (ALP), Alanine Aminotransferase (ALT), Aspartate Aminotransferase (AST) and serum electrolytes(Na+...