Evaluation Of Effects Of Aqueous Extracts Of Garlic (Allium Sativum) And Ginger (Zingiber Officinale) On Some Physiological Profiles Of Laboratory Animals

📄 Project Abstract

The aim of the study was to evaluate the effect of garlic (Allium sativum) and ginger (Zingiber officinale) on some heamato-biochemical parameters, blood pressure and their cardioprotective properties in laboratory animals. Wistar rats were assigned into seven (7) groups as mentioned below: Group 1: served as control group and received 1 ml/kg of distilled water, Group 2: received 20 mg/kg of garlic, Group 3: received 40 mg/kg of garlic; Group 4: received 20 mg/kg of ginger; Group 5: received 40 mg/kg of ginger; Group 6: received 10 mg/kg of garlic and 10 mg/kg ginger; Group 7: received 20 mg/kg of garlic and 20 mg/kg of ginger. All administrations were given orally once daily for a period of 28 days. At the end of the treatment, all animals were sacrificed; blood samples collected and the serum separated for determination of liver enzymes activities, lipid profile assay, biochemical and heamatological parameters. The liver tissue was excised and subjected to routine histological inves...