Evaluation Of Biomarkers Of Calcium Regulation And Oxidative Stress Among Pregnant And Lactating Women In Zaria, Nigeria

📄 Project Abstract

Pregnancy and lactation are normal but stressful physiological phenomena during which many biochemical changes occur, including calcium and phosphate metabolism, which may lead to calcium deficiency in pregnant women. Also the oxidative stress (ODS) associated with pregnancy and lactation induces increased activity of biomarkers of ODS. Since data on the serum levels of calcium, phosphate and ODS biomarkers in women in Zaria are scanty, the evaluation of their serum profiles in pregnant and lactating women in Zaria will provide reference data for clinicians and other medical workers involved in routine antenatal care in Nigeria and other resource limited third world countries. The aim of this study was to evaluate the changes in serum levels of calcium, phosphate, vitamin D and their regulatory hormones and serum antioxidant status of pregnant women in Zaria, Nigeria. In this study, blood samples were collected and anthropometric measurements such as weight, height and body mass index ...