DEVELOPMENT OF A FILLER-BINDER DISINTEGRANT FOR DIRECT COMPRESSION TABLETING BY CO-PROCESSING MICROCRYSTALLINE CELLULOSE AND CROSPOVIDONE
📄 Project Abstract
The aim of the study was to improve the disintegration functionality of microcrystalline cellulose (MCC) as a direct compression excipient in tablet formulation by coprocessing MCCwith crospovidone (CPV), a superdisintegrant. Design of Experiment (DoE) approach was adopted to optimize the composition of the co-processed excipient (CPE). The optimized CPE containing MCC (99 %) and CPV (1 %) was prepared using wet massing technique. Solid-state properties of CPE were characterized in comparison to MCC and CPV using optical and scanning electron microscopy (SEM), Powder XRay Diffraction (PXRD), Differential Scanning Calorimetry (DSC) and Fourier Transform Infra-red spectroscopy (FT-IR). Powder properties such as flowability, compressibility, moisture sorption capacity, moisture content, dilution potential and lubricant sensitivity ratio (LSR) were also evaluated using standard techniques. Compaction studies were carried out using Heckel and Kawakita equations as well as compressibility-ta...
🔍 Key Research Areas Covered
- ✅ Literature Review & Theoretical Framework
- ✅ Research Methodology & Data Collection
- ✅ Data Analysis & Statistical Methods
- ✅ Findings & Results Discussion
- ✅ Recommendations & Conclusions
- ✅ References & Bibliography
📚 Complete Project Structure
- Problem Statement & Objectives
- Theoretical Framework & Related Studies
- Data Collection & Analysis Methods
- Findings & Statistical Analysis
- Recommendations & Future Research
- Questionnaires, Data, References
⭐ Why Choose This Pharmaceutical And Medicinal Chemistry Project Topics Project?
🎯 Well-Researched
Thoroughly researched with current and relevant sources
📊 Complete Data
Includes statistical analysis and detailed findings
✍️ Original Content
100% original research with proper citations
📝 Properly Formatted
APA/MLA formatting with table of contents
🎓 Supervisor Approved
Meets university standards and requirements
⚡ Instant Download
Immediate access after purchase
🔗 Related Pharmaceutical And Medicinal Chemistry Project Topics Project Topics
💬 What Students Say
"This project provided excellent guidance for my Pharmaceutical And Medicinal Chemistry Project Topics research. The methodology was clear and the data analysis helped me understand the proper approach."
DEVELOPMENT OF A FILLER-BINDER DISINTEGRANT FOR DIRECT COMPRESSION TABLETING BY CO-PROCESSING MICROCRYSTALLINE CELLULOSE AND CROSPOVIDONE
Full Citation:
Fatima Haruna. (). DEVELOPMENT OF A FILLER-BINDER DISINTEGRANT FOR DIRECT COMPRESSION TABLETING BY CO-PROCESSING MICROCRYSTALLINE CELLULOSE AND CROSPOVIDONE. African and General Studies, 40, 14858.
Citation Formats:
APA
Fatima Haruna. (). DEVELOPMENT OF A FILLER-BINDER DISINTEGRANT FOR DIRECT COMPRESSION TABLETING BY CO-PROCESSING MICROCRYSTALLINE CELLULOSE AND CROSPOVIDONE. African and General Studies, 40, 14858.
MLA
Fatima Haruna. "DEVELOPMENT OF A FILLER-BINDER DISINTEGRANT FOR DIRECT COMPRESSION TABLETING BY CO-PROCESSING MICROCRYSTALLINE CELLULOSE AND CROSPOVIDONE." African and General Studies, vol. 40, , pp. 14858.
Chicago
Fatima Haruna. "DEVELOPMENT OF A FILLER-BINDER DISINTEGRANT FOR DIRECT COMPRESSION TABLETING BY CO-PROCESSING MICROCRYSTALLINE CELLULOSE AND CROSPOVIDONE." African and General Studies 40 (): 14858.
Full Citation:
Fatima Haruna. (). DEVELOPMENT OF A FILLER-BINDER DISINTEGRANT FOR DIRECT COMPRESSION TABLETING BY CO-PROCESSING MICROCRYSTALLINE CELLULOSE AND CROSPOVIDONE. African and General Studies, 40, 14858.
Citation Formats:
APA
Fatima Haruna. (). DEVELOPMENT OF A FILLER-BINDER DISINTEGRANT FOR DIRECT COMPRESSION TABLETING BY CO-PROCESSING MICROCRYSTALLINE CELLULOSE AND CROSPOVIDONE. African and General Studies, 40, 14858.
MLA
Fatima Haruna. "DEVELOPMENT OF A FILLER-BINDER DISINTEGRANT FOR DIRECT COMPRESSION TABLETING BY CO-PROCESSING MICROCRYSTALLINE CELLULOSE AND CROSPOVIDONE." African and General Studies, vol. 40, , pp. 14858.
Chicago
Fatima Haruna. "DEVELOPMENT OF A FILLER-BINDER DISINTEGRANT FOR DIRECT COMPRESSION TABLETING BY CO-PROCESSING MICROCRYSTALLINE CELLULOSE AND CROSPOVIDONE." African and General Studies 40 (): 14858.
Document Details
| Author | Fatima Haruna |
|---|---|
| 📁 Field | Pharmaceutical And Medicinal Chemistry Project Topics |
| 🏷️ Type | Pharmaceutical Sciences Project Topics |
| Pages | 133 Pages |
| Words | 25950 words |
| 📘 Chapters | 1 to 5 Chapters |