DEVELOPMENT AND VALIDATION OF SPECTROPHOTOMETRIC METHODS FOR THE DETERMINATION OF RISPERIDONE IN PURE AND TABLET DOSAGE FORMS
📄 Project Abstract
Two simple, sensitive, accurate and extraction-free spectrophotometric methods were developed and described for the determination of risperidone in pure and in tablet dosage forms. The methods are based on the formation of ion-pair complex between risperidone and the dyes bromocresol green in method A and thymol blue in method B at room temperature to form yellow coloured products having absorption maxima at 414 nm and 404 nm respectively. The composition of the ion-pairs was established by Jobs method and it was found to be 1:1 for both methods. Different variables affecting the reaction conditions such as diluting solvents, concentration of dye, reaction time were studied and optimized. Under the optimal conditions, linear relationship with good correlation coefficients (0.994 and 0.995 for methods A and B respectively) was found between absorbance and the concentrations of risperidone in the range of 2-20 g/ml and 20-40 g/ml respectively. The assay limits of detection (LOD) and limi...
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- ✅ Literature Review & Theoretical Framework
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- ✅ Data Analysis & Statistical Methods
- ✅ Findings & Results Discussion
- ✅ Recommendations & Conclusions
- ✅ References & Bibliography
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- Problem Statement & Objectives
- Theoretical Framework & Related Studies
- Data Collection & Analysis Methods
- Findings & Statistical Analysis
- Recommendations & Future Research
- Questionnaires, Data, References
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DEVELOPMENT AND VALIDATION OF SPECTROPHOTOMETRIC METHODS FOR THE DETERMINATION OF RISPERIDONE IN PURE AND TABLET DOSAGE FORMS
Full Citation:
Rukayyat Bukola Oloyede,. (). DEVELOPMENT AND VALIDATION OF SPECTROPHOTOMETRIC METHODS FOR THE DETERMINATION OF RISPERIDONE IN PURE AND TABLET DOSAGE FORMS. African and General Studies, 40, 14858.
Citation Formats:
APA
Rukayyat Bukola Oloyede,. (). DEVELOPMENT AND VALIDATION OF SPECTROPHOTOMETRIC METHODS FOR THE DETERMINATION OF RISPERIDONE IN PURE AND TABLET DOSAGE FORMS. African and General Studies, 40, 14858.
MLA
Rukayyat Bukola Oloyede,. "DEVELOPMENT AND VALIDATION OF SPECTROPHOTOMETRIC METHODS FOR THE DETERMINATION OF RISPERIDONE IN PURE AND TABLET DOSAGE FORMS." African and General Studies, vol. 40, , pp. 14858.
Chicago
Rukayyat Bukola Oloyede,. "DEVELOPMENT AND VALIDATION OF SPECTROPHOTOMETRIC METHODS FOR THE DETERMINATION OF RISPERIDONE IN PURE AND TABLET DOSAGE FORMS." African and General Studies 40 (): 14858.
Full Citation:
Rukayyat Bukola Oloyede,. (). DEVELOPMENT AND VALIDATION OF SPECTROPHOTOMETRIC METHODS FOR THE DETERMINATION OF RISPERIDONE IN PURE AND TABLET DOSAGE FORMS. African and General Studies, 40, 14858.
Citation Formats:
APA
Rukayyat Bukola Oloyede,. (). DEVELOPMENT AND VALIDATION OF SPECTROPHOTOMETRIC METHODS FOR THE DETERMINATION OF RISPERIDONE IN PURE AND TABLET DOSAGE FORMS. African and General Studies, 40, 14858.
MLA
Rukayyat Bukola Oloyede,. "DEVELOPMENT AND VALIDATION OF SPECTROPHOTOMETRIC METHODS FOR THE DETERMINATION OF RISPERIDONE IN PURE AND TABLET DOSAGE FORMS." African and General Studies, vol. 40, , pp. 14858.
Chicago
Rukayyat Bukola Oloyede,. "DEVELOPMENT AND VALIDATION OF SPECTROPHOTOMETRIC METHODS FOR THE DETERMINATION OF RISPERIDONE IN PURE AND TABLET DOSAGE FORMS." African and General Studies 40 (): 14858.
Document Details
| Author | Rukayyat Bukola Oloyede, |
|---|---|
| 📁 Field | Pharmaceutical And Medicinal Chemistry Project Topics |
| 🏷️ Type | Pharmaceutical Sciences Project Topics |
| Pages | 73 Pages |
| Words | 11942 words |
| 📘 Chapters | 1 to 5 Chapters |