COMPARISON OF THE INFLUENCES OF CHLOROQUINE AND CIMETIDINE ON THE PHARMACOKINETICS OF PARACETAMOL IN HEALTHY HUMAN SUBJECTS

You have 10 free previews remaining
Previews reset on:
Preview attempts remaining: 10 10 remaining

📄 Project Abstract

Malaria is very prevalent in the world especially in Africa and chloroquine is still a leading drug in the treatment of this ailment. Patients go to hospital with multiple illnesses, malaria inclusive. Thus other drugs are frequently prescribed with chloroquine. This work is designed to find out the interaction of chloroquine with other drugs with which it is commonly prescribed. This effect is compared with that of cimetidine on paracetamol absorption. Paracetamol (1g) was given orally alone as control (first stage). Cimetidine (400mg) was given concurrently with paracetamol (1g) orally (second stage) and then cimetidine was given orally one and a half hours before paracetamol (third stage). Chloroquine sulphate (0.8g) was given orally one and a half hours before paracetamol (fourth stage). All pharmacokinetic parameters of paracetamol were determined statistically for all the different stages of the study. They were then compared with control and those of chloroquine treated compared...

🔍 Key Research Areas Covered
  • ✅ Literature Review & Theoretical Framework
  • ✅ Research Methodology & Data Collection
  • ✅ Data Analysis & Statistical Methods
  • ✅ Findings & Results Discussion
  • ✅ Recommendations & Conclusions
  • ✅ References & Bibliography
📚 Complete Project Structure
Chapter 1: Introduction & Background
  • Problem Statement & Objectives
Chapter 2: Literature Review
  • Theoretical Framework & Related Studies
Chapter 3: Research Methodology
  • Data Collection & Analysis Methods
Chapter 4: Data Analysis & Results
  • Findings & Statistical Analysis
Chapter 5: Discussion & Conclusion
  • Recommendations & Future Research
Appendices: Supporting Documents
  • Questionnaires, Data, References
⭐ Why Choose This Pharmaceutical And Medicinal Chemistry Project Topics Project?
🎯 Well-Researched

Thoroughly researched with current and relevant sources

📊 Complete Data

Includes statistical analysis and detailed findings

✍️ Original Content

100% original research with proper citations

📝 Properly Formatted

APA/MLA formatting with table of contents

🎓 Supervisor Approved

Meets university standards and requirements

⚡ Instant Download

Immediate access after purchase

💬 What Students Say

"This project provided excellent guidance for my Pharmaceutical And Medicinal Chemistry Project Topics research. The methodology was clear and the data analysis helped me understand the proper approach."

— Final Year Student, Pharmaceutical Sciences Project Topics
Full Citation:

Amina Sani Yakasai. (). COMPARISON OF THE INFLUENCES OF CHLOROQUINE AND CIMETIDINE ON THE PHARMACOKINETICS OF PARACETAMOL IN HEALTHY HUMAN SUBJECTS. African and General Studies, 40, 14858.

Citation Formats:
APA
Amina Sani Yakasai. (). COMPARISON OF THE INFLUENCES OF CHLOROQUINE AND CIMETIDINE ON THE PHARMACOKINETICS OF PARACETAMOL IN HEALTHY HUMAN SUBJECTS. African and General Studies, 40, 14858.
MLA
Amina Sani Yakasai. "COMPARISON OF THE INFLUENCES OF CHLOROQUINE AND CIMETIDINE ON THE PHARMACOKINETICS OF PARACETAMOL IN HEALTHY HUMAN SUBJECTS." African and General Studies, vol. 40, , pp. 14858.
Chicago
Amina Sani Yakasai. "COMPARISON OF THE INFLUENCES OF CHLOROQUINE AND CIMETIDINE ON THE PHARMACOKINETICS OF PARACETAMOL IN HEALTHY HUMAN SUBJECTS." African and General Studies 40 (): 14858.
Full Citation:

Amina Sani Yakasai. (). COMPARISON OF THE INFLUENCES OF CHLOROQUINE AND CIMETIDINE ON THE PHARMACOKINETICS OF PARACETAMOL IN HEALTHY HUMAN SUBJECTS. African and General Studies, 40, 14858.

Citation Formats:
APA
Amina Sani Yakasai. (). COMPARISON OF THE INFLUENCES OF CHLOROQUINE AND CIMETIDINE ON THE PHARMACOKINETICS OF PARACETAMOL IN HEALTHY HUMAN SUBJECTS. African and General Studies, 40, 14858.
MLA
Amina Sani Yakasai. "COMPARISON OF THE INFLUENCES OF CHLOROQUINE AND CIMETIDINE ON THE PHARMACOKINETICS OF PARACETAMOL IN HEALTHY HUMAN SUBJECTS." African and General Studies, vol. 40, , pp. 14858.
Chicago
Amina Sani Yakasai. "COMPARISON OF THE INFLUENCES OF CHLOROQUINE AND CIMETIDINE ON THE PHARMACOKINETICS OF PARACETAMOL IN HEALTHY HUMAN SUBJECTS." African and General Studies 40 (): 14858.
Need Help?