COMPARISON OF THE INFLUENCES OF CHLOROQUINE AND CIMETIDINE ON THE PHARMACOKINETICS OF PARACETAMOL IN HEALTHY HUMAN SUBJECTS
📄 Project Abstract
Malaria is very prevalent in the world especially in Africa and chloroquine is still a leading drug in the treatment of this ailment. Patients go to hospital with multiple illnesses, malaria inclusive. Thus other drugs are frequently prescribed with chloroquine. This work is designed to find out the interaction of chloroquine with other drugs with which it is commonly prescribed. This effect is compared with that of cimetidine on paracetamol absorption. Paracetamol (1g) was given orally alone as control (first stage). Cimetidine (400mg) was given concurrently with paracetamol (1g) orally (second stage) and then cimetidine was given orally one and a half hours before paracetamol (third stage). Chloroquine sulphate (0.8g) was given orally one and a half hours before paracetamol (fourth stage). All pharmacokinetic parameters of paracetamol were determined statistically for all the different stages of the study. They were then compared with control and those of chloroquine treated compared...
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- ✅ Literature Review & Theoretical Framework
- ✅ Research Methodology & Data Collection
- ✅ Data Analysis & Statistical Methods
- ✅ Findings & Results Discussion
- ✅ Recommendations & Conclusions
- ✅ References & Bibliography
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- Problem Statement & Objectives
- Theoretical Framework & Related Studies
- Data Collection & Analysis Methods
- Findings & Statistical Analysis
- Recommendations & Future Research
- Questionnaires, Data, References
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Full Citation:
Amina Sani Yakasai. (). COMPARISON OF THE INFLUENCES OF CHLOROQUINE AND CIMETIDINE ON THE PHARMACOKINETICS OF PARACETAMOL IN HEALTHY HUMAN SUBJECTS. African and General Studies, 40, 14858.
Citation Formats:
APA
Amina Sani Yakasai. (). COMPARISON OF THE INFLUENCES OF CHLOROQUINE AND CIMETIDINE ON THE PHARMACOKINETICS OF PARACETAMOL IN HEALTHY HUMAN SUBJECTS. African and General Studies, 40, 14858.
MLA
Amina Sani Yakasai. "COMPARISON OF THE INFLUENCES OF CHLOROQUINE AND CIMETIDINE ON THE PHARMACOKINETICS OF PARACETAMOL IN HEALTHY HUMAN SUBJECTS." African and General Studies, vol. 40, , pp. 14858.
Chicago
Amina Sani Yakasai. "COMPARISON OF THE INFLUENCES OF CHLOROQUINE AND CIMETIDINE ON THE PHARMACOKINETICS OF PARACETAMOL IN HEALTHY HUMAN SUBJECTS." African and General Studies 40 (): 14858.
Full Citation:
Amina Sani Yakasai. (). COMPARISON OF THE INFLUENCES OF CHLOROQUINE AND CIMETIDINE ON THE PHARMACOKINETICS OF PARACETAMOL IN HEALTHY HUMAN SUBJECTS. African and General Studies, 40, 14858.
Citation Formats:
APA
Amina Sani Yakasai. (). COMPARISON OF THE INFLUENCES OF CHLOROQUINE AND CIMETIDINE ON THE PHARMACOKINETICS OF PARACETAMOL IN HEALTHY HUMAN SUBJECTS. African and General Studies, 40, 14858.
MLA
Amina Sani Yakasai. "COMPARISON OF THE INFLUENCES OF CHLOROQUINE AND CIMETIDINE ON THE PHARMACOKINETICS OF PARACETAMOL IN HEALTHY HUMAN SUBJECTS." African and General Studies, vol. 40, , pp. 14858.
Chicago
Amina Sani Yakasai. "COMPARISON OF THE INFLUENCES OF CHLOROQUINE AND CIMETIDINE ON THE PHARMACOKINETICS OF PARACETAMOL IN HEALTHY HUMAN SUBJECTS." African and General Studies 40 (): 14858.
Document Details
| Author | Amina Sani Yakasai |
|---|---|
| 📁 Field | Pharmaceutical And Medicinal Chemistry Project Topics |
| 🏷️ Type | Pharmaceutical Sciences Project Topics |
| Pages | 131 Pages |
| Words | 486 words |
| 📘 Chapters | 1 to 5 Chapters |