COMPARATIVE IN-VITRO BIOEQUIVALENCE STUDIES OF SOME BRANDS OF METRONIDAZOLE TABLET MARKETED IN ZARIA, KADUNA STATE

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📄 Project Abstract

Metronidazole is an antibacterial and antiprotozoal drug used in the treatment of amebiasis, giardiasis, trichomoniasis and other microbial diseases. It is an essential drug commonly found in Nigerian market and has so many generics and dosage forms under various trade names by different manufacturers. The purpose of the study was to evaluate and compare the in-vitro bioequivalence of branded and generic metronidazole tablet in three different physiological media (pH 1.2, 4.5 and 6.8). Six brands of metronidazole tablet were randomly selected from different areas of Zaria town and evaluated for quality via identification test, assay, weight variation test, disintegration time test, friability, crushing strength and dissolution. Three UV spectrophotometric methods were developed, validated and used for determining the amount of metronidazole release during the in-vitro dissolution studies. The percentage of metronidazole released was then subjected to in-vitro bioequivalence comparison ...

🔍 Key Research Areas Covered
  • ✅ Literature Review & Theoretical Framework
  • ✅ Research Methodology & Data Collection
  • ✅ Data Analysis & Statistical Methods
  • ✅ Findings & Results Discussion
  • ✅ Recommendations & Conclusions
  • ✅ References & Bibliography
📚 Complete Project Structure
Chapter 1: Introduction & Background
  • Problem Statement & Objectives
Chapter 2: Literature Review
  • Theoretical Framework & Related Studies
Chapter 3: Research Methodology
  • Data Collection & Analysis Methods
Chapter 4: Data Analysis & Results
  • Findings & Statistical Analysis
Chapter 5: Discussion & Conclusion
  • Recommendations & Future Research
Appendices: Supporting Documents
  • Questionnaires, Data, References
⭐ Why Choose This Pharmaceutical And Medicinal Chemistry Project Topics Project?
🎯 Well-Researched

Thoroughly researched with current and relevant sources

📊 Complete Data

Includes statistical analysis and detailed findings

✍️ Original Content

100% original research with proper citations

📝 Properly Formatted

APA/MLA formatting with table of contents

🎓 Supervisor Approved

Meets university standards and requirements

⚡ Instant Download

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💬 What Students Say

"This project provided excellent guidance for my Pharmaceutical And Medicinal Chemistry Project Topics research. The methodology was clear and the data analysis helped me understand the proper approach."

— Final Year Student, Pharmaceutical Sciences Project Topics
Full Citation:

Mujitapha Fatima Malumfashi. (). COMPARATIVE IN-VITRO BIOEQUIVALENCE STUDIES OF SOME BRANDS OF METRONIDAZOLE TABLET MARKETED IN ZARIA, KADUNA STATE. African and General Studies, 40, 14858.

Citation Formats:
APA
Mujitapha Fatima Malumfashi. (). COMPARATIVE IN-VITRO BIOEQUIVALENCE STUDIES OF SOME BRANDS OF METRONIDAZOLE TABLET MARKETED IN ZARIA, KADUNA STATE. African and General Studies, 40, 14858.
MLA
Mujitapha Fatima Malumfashi. "COMPARATIVE IN-VITRO BIOEQUIVALENCE STUDIES OF SOME BRANDS OF METRONIDAZOLE TABLET MARKETED IN ZARIA, KADUNA STATE." African and General Studies, vol. 40, , pp. 14858.
Chicago
Mujitapha Fatima Malumfashi. "COMPARATIVE IN-VITRO BIOEQUIVALENCE STUDIES OF SOME BRANDS OF METRONIDAZOLE TABLET MARKETED IN ZARIA, KADUNA STATE." African and General Studies 40 (): 14858.
Full Citation:

Mujitapha Fatima Malumfashi. (). COMPARATIVE IN-VITRO BIOEQUIVALENCE STUDIES OF SOME BRANDS OF METRONIDAZOLE TABLET MARKETED IN ZARIA, KADUNA STATE. African and General Studies, 40, 14858.

Citation Formats:
APA
Mujitapha Fatima Malumfashi. (). COMPARATIVE IN-VITRO BIOEQUIVALENCE STUDIES OF SOME BRANDS OF METRONIDAZOLE TABLET MARKETED IN ZARIA, KADUNA STATE. African and General Studies, 40, 14858.
MLA
Mujitapha Fatima Malumfashi. "COMPARATIVE IN-VITRO BIOEQUIVALENCE STUDIES OF SOME BRANDS OF METRONIDAZOLE TABLET MARKETED IN ZARIA, KADUNA STATE." African and General Studies, vol. 40, , pp. 14858.
Chicago
Mujitapha Fatima Malumfashi. "COMPARATIVE IN-VITRO BIOEQUIVALENCE STUDIES OF SOME BRANDS OF METRONIDAZOLE TABLET MARKETED IN ZARIA, KADUNA STATE." African and General Studies 40 (): 14858.
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