Comparative Evaluation Of Antibody Production In Broilers Vaccinated With Newcastle Disease Vaccines In Kano Metropolis, Nigeria

📄 Project Abstract

The incidence of Newcastle disease (ND) in Nigeria is high and is a persistent cause of mortality and (or) morbidity among vaccinated chickens causing huge economic losses. This study was carried out to evaluate the persistence of maternally derived antibody (MDA) against Newcastle Disease Virus (NDV), thermo-stability of the test vaccines, comparative analysis of humoral immune response against four La Sota NDV vaccines as well as the effect of time with respect to vaccination schedule. In study group I; four experimental groups A, B, C and D each which consisted of 10 birds were vaccinated with corresponding vaccines on day 14 (primer) and 28 (booster) and group E of 10 birds was maintained as unvaccinated control. Serum samples collected from five randomly selected birds among the vaccinated groups on day 17, 21, 24, 28 and 35 and from the unvaccinated group E on day 1, 3, 10, 14, 24, 28 and 35 were subjected to haemagglutination inhibition (HI) titre test. Study group II; two exper...