COMPARATIVE BIOEQUIVALENCE STUDIES OF SOME BRANDS OF METRONIDAZOLE TABLETS MARKETED IN ZARIA, NIGERIA
📄 Project Abstract
Multisource pharmaceutical products are intended to be pharmaceutically equivalent or pharmaceutical alternatives that are bioequivalent and hence are therapeutically equivalent and interchangeable. Thus, this study was aimed at carrying out a comparative in-vitro and in-vivo bioequivalence studies of some brands of Metronidazole (200 mg) tablets marketed in Zaria, Nigeria. BP 2002 method was use for the assessment of the pharmaceutical and chemical equivalences of the samples of metronidazole tablets. Tablet hardness and friability testing were also carried out to reinforce the official methods for the in vitro studies. The analytical method for the in vivo studies was adopted from the work of Kolawole and Ameh (2004). The method was validated according to ICH/WHO guideline. Six healthy human volunteers were enrolled for the studies according to the normal protocols for bioequivalence studies. The study yielded the following results: The presence of metronidazole was observed in all t...
🔍 Key Research Areas Covered
- ✅ Literature Review & Theoretical Framework
- ✅ Research Methodology & Data Collection
- ✅ Data Analysis & Statistical Methods
- ✅ Findings & Results Discussion
- ✅ Recommendations & Conclusions
- ✅ References & Bibliography
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- Problem Statement & Objectives
- Theoretical Framework & Related Studies
- Data Collection & Analysis Methods
- Findings & Statistical Analysis
- Recommendations & Future Research
- Questionnaires, Data, References
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Full Citation:
Shuaibualiyu, B.. (). COMPARATIVE BIOEQUIVALENCE STUDIES OF SOME BRANDS OF METRONIDAZOLE TABLETS MARKETED IN ZARIA, NIGERIA. African and General Studies, 40, 14858.
Citation Formats:
APA
Shuaibualiyu, B.. (). COMPARATIVE BIOEQUIVALENCE STUDIES OF SOME BRANDS OF METRONIDAZOLE TABLETS MARKETED IN ZARIA, NIGERIA. African and General Studies, 40, 14858.
MLA
Shuaibualiyu, B.. "COMPARATIVE BIOEQUIVALENCE STUDIES OF SOME BRANDS OF METRONIDAZOLE TABLETS MARKETED IN ZARIA, NIGERIA." African and General Studies, vol. 40, , pp. 14858.
Chicago
Shuaibualiyu, B.. "COMPARATIVE BIOEQUIVALENCE STUDIES OF SOME BRANDS OF METRONIDAZOLE TABLETS MARKETED IN ZARIA, NIGERIA." African and General Studies 40 (): 14858.
Full Citation:
Shuaibualiyu, B.. (). COMPARATIVE BIOEQUIVALENCE STUDIES OF SOME BRANDS OF METRONIDAZOLE TABLETS MARKETED IN ZARIA, NIGERIA. African and General Studies, 40, 14858.
Citation Formats:
APA
Shuaibualiyu, B.. (). COMPARATIVE BIOEQUIVALENCE STUDIES OF SOME BRANDS OF METRONIDAZOLE TABLETS MARKETED IN ZARIA, NIGERIA. African and General Studies, 40, 14858.
MLA
Shuaibualiyu, B.. "COMPARATIVE BIOEQUIVALENCE STUDIES OF SOME BRANDS OF METRONIDAZOLE TABLETS MARKETED IN ZARIA, NIGERIA." African and General Studies, vol. 40, , pp. 14858.
Chicago
Shuaibualiyu, B.. "COMPARATIVE BIOEQUIVALENCE STUDIES OF SOME BRANDS OF METRONIDAZOLE TABLETS MARKETED IN ZARIA, NIGERIA." African and General Studies 40 (): 14858.
Document Details
| Author | Shuaibualiyu, B. |
|---|---|
| 📁 Field | Pharmaceutical And Medicinal Chemistry Project Topics |
| 🏷️ Type | Pharmaceutical Sciences Project Topics |
| Pages | 84 Pages |
| Words | 18046 words |
| 📘 Chapters | 1 to 5 Chapters |