Antibiotic Susceptibilities And Plasmid Profile Of Extended Spectrum Beta Lactamase- Producing Escherichia Coli From Community Acquired Urinary Tract Infection At The University Of Port Harcourt Teaching Hospital

📄 Project Abstract

Objectives - Globally, the emergence of Extended Spectrum Beta Lactamase (ESBL) producing Escherichia coli has been noted in community acquired strains as against the hospital acquired origin were it was more frequent in the past. This study was therefore designed to assess the antibiotic susceptibility pattern of Escherichia coli; the agent commonly isolated in community acquired urinary tract infection to the first line antibiotic in UPTH and to determine the Extended-Spectrum Beta Lactamase producers among the multidrug resistant E. coli strains. And to also detect plasmids associated with ESBL production in those isolates. This will enhance targeted anti-microbial management of community acquired UTI in University of Port Harcourt Teaching Hospital. Methods - Demographic data from patients suspected of having community acquired UTI were obtained with the aid of interviewer-administered questionnaires. Urine samples were cultured on MacConkey agar and Blood agar plates. Gram negativ...