Anti-Annexin V Levels And Haematological Indices In Sickle Cell Anaemia Patients In Vasooclusive Crisis At Lagos University Teaching Hospital
📄 Project Abstract
Background: Annexin V is a glycoprotein with anticoagulant activity. IgG and IgM Anti-AnnexinV antibodies have the ability to displace annexin V from phospholipid surfaces and this has been linked with enhanced prothrombotic conditions such as vasoocclusive crisis, the hallmark of SCA. Anti-annexin V antibodies have been strongly associated with VOC. The association of Anti-Annexin V antibodies and the extent of its rise in VOC is yet to be fully determined in Nigerians suffering from SCA. Objectives: To determine the levels of IgM and IgG antibodies to Annexin V in SCA in crisis and steady states in order to assess contribution of the procoagulant effect of Anti-Annexin V to vasoocclusive crisis and its severity. Materials and Methods: This is a cross sectional case control study. The study comprises of SCA subjects; 35 subjects in vasoocclusive crisis, 35 subjects in steady states and 20 HbAA control subjects. Anti-annexin V antibodies activity was determined with ELISA KIT (Lot numb...
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- Data Collection & Analysis Methods
- Findings & Statistical Analysis
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Anti-Annexin V Levels And Haematological Indices In Sickle Cell Anaemia Patients In Vasooclusive Crisis At Lagos University Teaching Hospital
Full Citation:
Edewor-Okiyo, Oghale Deborah. (). Anti-Annexin V Levels And Haematological Indices In Sickle Cell Anaemia Patients In Vasooclusive Crisis At Lagos University Teaching Hospital. African and General Studies, 40, 14858.
Citation Formats:
APA
Edewor-Okiyo, Oghale Deborah. (). Anti-Annexin V Levels And Haematological Indices In Sickle Cell Anaemia Patients In Vasooclusive Crisis At Lagos University Teaching Hospital. African and General Studies, 40, 14858.
MLA
Edewor-Okiyo, Oghale Deborah. "Anti-Annexin V Levels And Haematological Indices In Sickle Cell Anaemia Patients In Vasooclusive Crisis At Lagos University Teaching Hospital." African and General Studies, vol. 40, , pp. 14858.
Chicago
Edewor-Okiyo, Oghale Deborah. "Anti-Annexin V Levels And Haematological Indices In Sickle Cell Anaemia Patients In Vasooclusive Crisis At Lagos University Teaching Hospital." African and General Studies 40 (): 14858.
Full Citation:
Edewor-Okiyo, Oghale Deborah. (). Anti-Annexin V Levels And Haematological Indices In Sickle Cell Anaemia Patients In Vasooclusive Crisis At Lagos University Teaching Hospital. African and General Studies, 40, 14858.
Citation Formats:
APA
Edewor-Okiyo, Oghale Deborah. (). Anti-Annexin V Levels And Haematological Indices In Sickle Cell Anaemia Patients In Vasooclusive Crisis At Lagos University Teaching Hospital. African and General Studies, 40, 14858.
MLA
Edewor-Okiyo, Oghale Deborah. "Anti-Annexin V Levels And Haematological Indices In Sickle Cell Anaemia Patients In Vasooclusive Crisis At Lagos University Teaching Hospital." African and General Studies, vol. 40, , pp. 14858.
Chicago
Edewor-Okiyo, Oghale Deborah. "Anti-Annexin V Levels And Haematological Indices In Sickle Cell Anaemia Patients In Vasooclusive Crisis At Lagos University Teaching Hospital." African and General Studies 40 (): 14858.
Document Details
| Author | Edewor-Okiyo, Oghale Deborah |
|---|---|
| 📁 Field | Anatomic Pathology project topics |
| 🏷️ Type | Medicine Project topics |
| Pages | 65 Pages |
| Words | 13056 words |
| 📘 Chapters | 1 to 5 Chapters |