Anatomical And Immunohistochemical Studies Of The Spinal Cord Of The Grasscutter (Thryonomysswinderianus)

📄 Project Abstract

Grasscutters are currently being explored as laboratory models for scientific, medical and behavioural researches. In the present study, the anatomical, histological, histochemical and immunohistochemical studies of the spinal cord of the grasscutter was evaluated. Twelve adult Grasscutters comprising six males and six females were utilized for the study. The studies on the spinal cord of Grasscutter were done by gross observations and light microscopical methods. The animals were weighed and sacrificed by dissected. The spinal cords were removed by splitting open the vertebrae to expose the spinal cords which were then cleaned by removing the meninges surrounding them. The gross morphology of the spinal cord was studied while the segments were fixed, processed, sectioned and were taken for histological, histochemical and immunohistochemical studies using H and E, Cresyl fast violet, Golgi-Cox and Alpha-1 antityrosine hydroxylase methods respectively for detailed studies of the spinal ...