AN EVALUATION OF THE APHRODISIAC AND FERTILITY ENHANCING EFFECT OF THE METHANOLIC ROOT EXTRACT OF CISSUS POPULNEA Guill.And Perr. (Vitaceae)

📄 Project Abstract

Aphrodisiac activity of Cissus populnea was assessed using physical, biochemical and psychological methods. Rats were randomized into five groups of six rats. The first group received normal saline (10ml/kg), the second, third and fourth groups received extract doses of 250mg/kg, 500mg/kg and 1000mg/kg respectively while the fifth group received 5mg/kg of sildenafil citrate orally for 28 days. On the 24th day, the effect of the root extract of Cissus populnea (CPRE) on mounting and mating frequencies was evaluated. The psychological (mood) effect of CPRE was evaluated on the 27th day by exposing the treated rats to the elevated plus maze (EPM) for five (5) minutes and the time spent in the open and close arms of the EPM were recorded. On the 29th day, the rats were anaesthetized with diethylether and blood samples were collected by cardiac puncture for biochemical analysis (testosterone, cortisol, prostate specific antigen (PSA) levels, liver and kidney function parameters). Testes wer...